Who Supports Non-Animal Test Models?
One of my passions besides traveling is animals and when choosing a product I have always tried to buy from companies that are cruelty free. The products referred to on this site are made by a company that not only does not test on animals, but actively supports research on the developement of non animal alternatives. I would like to share with you an email on the subject that I just received from Dr. Steve Chaney Ph.D :
Aug.25 2009
Hi Susan,
While clinical studies are the gold standard for
determining the effectiveness of a drug or a nutrient,
it is sometimes difficult to avoid animal studies if
you want to determine how that drug or nutrient works.
And those basic “mechanism of action” studies are often
a necessary prelude to the clinical studies.
That is why Shaklee’s commitment not to use any animal
studies in the testing of their products is so
important.
If you are passionate about reducing the use of animals
in research, you will be particularly impressed with
Shaklee’s latest research project.
You see Shaklee wanted to do some basic research on how
Nutriferon works to prevent viral infections in the
lung. So they contacted scientists at Cornell
University to do those experiments.
Shaklee contacted those particular scientists to do the
experiments because they were world experts in the
field of immunology, and they were world experts in the
development of model systems that can be used in the
place of animal studies.
The scientists asked Shaklee if they would first
support their research in developing an animal-free
model system for determining how the airway epithelium
(in layman’s terms this refers to the layers of cells
that line the lungs and windpipe) responds to viral
infections.
Shaklee agreed to support the research at Cornell in
developing a model of the human airway epithelium -
even though that research itself did not involve any
Shaklee products and was, therefore, of no direct
benefit to Shaklee.
The Cornell scientists have published their first paper
using this human airway epithelium (HAE) model system.
(Palmero et al., Journal of Virology, 83: 6900-6908).
That particular paper showed how the lungs respond to a
particular type of parainfluenza virus that is
responsible for croup and bronchitis in children
Shaklee’s support in the development of the HAE model
system was acknowledged in that paper and will be
acknowledged in all future papers using that model
system.
Of course, the research didn’t stop there. Shaklee also
supported a research project by the same scientists to
determine how Nutriferon helps the lungs resist
infection by flu viruses.
I can’t release all of the results of that study yet
because the study has not yet been published. But I can
tell you that the study showed that Nutriferon
activates “natural killer cells” when a flu virus
infects lung tissue.
This is a significant finding because, as their name
suggests, natural killer cells play an important role
in “killing” the flu virus. We already knew that
Nutriferon helped fight viral infections, but we didn’t
know how. This research is an important part of the
proof that Nutriferon is effective.
In Summary:
1) Shaklee has supported fundamental research at
Cornell University into the development of a model
system that allows scientists to test how human lung
tissue responds to viral infections – and without the
use of animals.
2) This study is significant in itself because it will
allow scientists across the world to answer important
scientific questions that can not be addressed in
clinical trials – and the lives of many thousands of
laboratory animals will be spared in the process.
3) This is yet another example of Shaklee’s commitment
to supporting research that advances scientific
knowledge – not just research that can be used in the
marketing of their products. This commitment to true
science is unique among food supplement companies.
4) These same scientist went on to use this model
system to show that Nutriferon protects human lung
tissue from viral infection by activating natural
killer cells which destroy the virus.
5) This provides even stronger evidence of the
effectiveness of Nutriferon by showing how it works.
To your health!
Dr. Stephen Chaney, PhD – P. S. I’m sure that some of you are going to ask me
about the swine flu.
This study was not done with swine flu virus, so it
does not provide direct evidence that Nutriferon will
protect against the swine flu.
However, you should know that natural killer cells are
not particularly choosy. They destroy every virus that
they come across.
Thus, I consider Nutriferon to be an important part of
everyone’s health plan to reduce the risk of coming
down with the swine flu. I will address this and other
strategies for avoiding swine flu in my upcoming CD
“Tune-Up Your Immune System”.
Dr. Steve Chaney,Durham, NC 27713 United States 888.860.2075

